Phospho sting antibody

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August undefined, 2024

WebThe Phospho-STING (Ser366) assay uses 2 labeled antibodies: one with a donor fluorophore, the other one with an acceptor. The first antibody is selected for its specific binding to the phosphorylated motif on the protein, the second for its ability to recognize the protein independent of its phosphorylation state. WebDec 6, 2024 · We show for the first time that the STING pathway is activated in the lung of ILD patients, as seen by STING overexpression, phosphorylation and dimer formation, TBK1 and IRF3 phosphorylation,...

STING (Phospho-Ser366) Antibody - SAB Signalway Antibody

WebInhibition of IDH3α enhanced the efficacy of chemoimmunotherapy by activating cGAS-STING pathway through regulating acidic tumor microenvironments. Preprint on Research Square on 11 October 2024 by Zhang, L., Dai, X., et al.. WebFor Analyzing Cell Signaling Pathway Activation. Phosphorylation, the addition of a phosphate group to serine, threonine or tyrosine residues, is an important cellular process utilized to send cellular signals from the membrane to the nucleus. For example, changes in physiological conditions may require immediate changes in gene expression. ttl244

Phospho-STING/TMEM173-S366 Rabbit pAb (AP1223)

WebSTING (TMEM173), also called stimulator of interferon genes, is a transmembrane adaptor protein that plays an important role in the innate immune response against viral and bacterial infections. It has been shown that cyclic GMP-AMP synthase (cGAS) plays a key role in STING activation. WebWhen selecting a phospho-specific antibody for your experiments, it is crucial to ensure that the antibody specifically detects the protein of interest only when it is phosphorylated at the indicated site. It is also essential to check that the antibody detects a band at the correct molecular weight for your phosphorylated target protein. WebWip1 Aggravates the Cerulein-Induced Cell Autophagy and Inflammatory Injury by Targeting STING/TBK1/IRF3 in Acute Pancreatitis. In Inflammation on 1 June 2024 by Song, Y., … phoenix fire station 50

Phosphorylation of innate immune adaptor proteins MAVS, STING …

STING-dependent sensing of self-DNA drives silica-induced lung ... - Nature

WebCell Signaling Technology's Phospho-STING (Ser366) (D8K6H) Rabbit mAb (Alexa Fluor ® 647 Conjugate) is a Rabbit monoclonal antibody. The Phospho-STING (Ser366) (D8K6H) … WebAll lanes : Anti-Phospho - (Ser/Thr) Phe antibody (ab17464) at 1/1000 dilution Lane 1 : Human THP-1 Whole Cell Extract Lane 2 : Mouse Total Lung Extract Lysates/proteins at … ttl118WebMar 25, 2024 · Storage : -20°C. Description : STING is a 379 amino acid containing signaling protein that acts as an important component of innate immune signaling. This signaling protein is able to activate both NF-kappa-B and IRF3 transcription pathways to induce expression of type I interferon (IFN-alpha and IFN-beta) and exert a potent anti-viral state ... ttl 21600

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Phospho sting antibody

Human Monocyte STING Activation Flow Cytometry Panel

WebProduct name Anti-STING antibody [SP338] See all STING primary antibodies Description Rabbit monoclonal [SP338] to STING Host species Rabbit Tested applications Suitable … WebCell Signaling Technology's Phospho-STING (Ser366) (D8K6H) Rabbit mAb (Alexa Fluor ® 647 Conjugate) is a Rabbit monoclonal antibody. The Phospho-STING (Ser366) (D8K6H) Rabbit mAb (Alexa Fluor ® 647 Conjugate) Antibody was generated using stimulator of interferon response cGAMP interactor 1, and STING1 as the antigen. It reacts with …

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Web产品说明. The Human Monocyte STING Activation Flow Cytometry Panel includes antibodies targeting phospho-STING (Ser366) and phenotyping markers to enable observation of STING activation in human monocyte populations among peripheral blood mononuclear cells (PBMCs). CD45 is a pan leukocyte marker. Monocytes and dendritic … Web55. A method of treating, inhibiting, reducing, ameliorating, and/or preventing a cancer and or metastasis in a subject comprising administering to a subject an adoptive immunothe

WebThe antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns. Storage: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt. Alias: Fold/Unfold WebPhospho-STING-Ser366 polyclonal antibody (Stimulator of interferon genes protein) binds to endogenous Stimulator of interferon genes protein only when phosphorylated at Ser366. Phosphorylation by TBK1 leads to activation and production of IFN-beta. Following cyclic nucleotide (c-di-GMP or cGAMP)-binding, activation and translocation from the ...

WebPhospho-STING (Ser366) Polyclonal Antibody Product Details Size 100 µL Species Reactivity Human, Mouse, Rat Host / Isotype Rabbit / IgG Class Polyclonal Type Antibody Conjugate Unconjugated Immunogen A synthesized peptide derived from human STING around the phosphorylation site of Ser366. Form Liquid Concentration 1mg/mL WebPhospho-STING (Ser365) Antibody (PA5-117271) in WB Western blot analysis of extracts of THP-1 cells using Phospho-STING (Ser365) Polyclonal Antibody (Product # PA5-117271). …

WebPhospho-STING (Ser366) (D8K6H) Rabbit mAb (Alexa Fluor® 647 Conjugate) recognizes endogenous levels of STING protein only when phosphorylated at Ser366. Source/Purification: Monoclonal antibodies were purified from tissue culture supernatant via affinity chromatography. The purified antibodies were conjugated under optimal condi-

WebCell Signaling Technology's Phospho-STING (Ser366) (D8K6H) Rabbit mAb is a Rabbit monoclonal antibody. The Phospho-STING (Ser366) (D8K6H) Rabbit mAb Antibody was generated using stimulator of interferon response cGAMP interactor 1, and STING1 as the antigen. It reacts with Human. This antibody has been shown to work in applications such … ttl 225WebWestern blot analysis of THP-1, using Phospho-STING/TMEM173-S366 antibody (AP1223) at 1:600 dilution.THP-1 cells were transfection with poly (dA:dT) (5ug/mL) for 3 hours. Secondary antibody: HRP Goat Anti-Rabbit … ttl 228WebPolyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Ser366 of human STING protein. Antibodies are purified by protein A and peptide affinity chromatography. Validations. None provided. Applications. Immunoprecipitation (IP) Western Blotting (WB) Reactivity. Homo sapiens … phoenix first assembly of god tommy barnettWebPurification The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns. Applications WB … phoenix fire tokenWebSep 30, 2024 · A polyclonal antibody against phospho-S365 of mouse STING was generated in rabbits and affinity-purified (Fig. S2E). Polyclonal antibodies against mouse STING, Igα, Igβ, class I MHC heavy chain ... phoenix-firestorm-releasex64WebPhospho-STING (Ser366) (D7C3S) Rabbit mAb recognizes endogenous levels of STING protein only when phosphorylated at Ser366. Species Reactivity: Human Source / … ttl 200WebPhosphospecific antibodies are affinity-purified rabbit polyclonal or monoclonal antibodies that are monospecific for a target protein that is phosphorylated. These antibodies provide critical insight into the investigation of complex signal transductions events. On this page Why use phosphospecific antibodies? ttl 20