Cisplatin h460
WebApr 9, 2024 · However, in the H460 cell line with the low basal expression level of SNRPB, overexpressing of SNRPB markedly increased cisplatin-induced cell proliferation … WebDec 16, 2015 · H460 lung cancer cells increased cisplatin sensitivity and showed reduced repair of both . intrastrand and interstrand adducts suggesting that the mechanism of sensitivity is primarily .
Cisplatin h460
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WebResistance mechanism to cisplatin in NCI-H460 non-small cell lung cancer cell line: investigating apoptosis, autophagy, and cytogenetic damage … WebLung cancer is a malignant tumor characterized by a rapid proliferation rate, less survivability, high mortality, and metastatic potential. This review focuses on updated research about the clinical application of traditional Chinese medicine (TCM) as an adjuvant therapy to lung cancer treatment and the mechanisms of TCM effect on lung cancer in …
WebC is-diamminedichloroplatinum(II) (cisplatin) is the most celebrated metal-based chemotherapeutic in the history of modern medicine.The discovery of its anticancer effects was not only opportune [1,2,3], especially during a period when cancer prevention was desperately needed, but also because medical oncology did not yet exist as a clinical … WebCisplatin may cause severe kidney problems, nerve problems, and severe nausea and vomiting. Nerve problems may occur during treatment or weeks after stopping treatment.
WebJan 26, 2024 · Emodin enhances cisplatin-induced DNA damage in A549 and H460 cells Cisplatin mainly kills tumor cells by inducing DNA damage ( 30 ). The effect of emodin on the chemosensitivity of A549 and H460 … WebOct 31, 2024 · Generation of Cisplatin-Resistant Lung Cancer Cell Lines A549, H460, H661, and H1299 lung cancer cells were exposed to cisplatin according to the IC50 value for 72 h. The medium was removed, and the cells were cultured in normal medium until the cells fully recovered.
Web检测H460细胞中p-Akt蛋白的表达。将细胞接种于6孔板中，加入不同浓度(10、20、30 μmol/L)芝麻素处理12 h后，在每孔细胞中加入100 μL的蛋白裂解液后，采用BCA试剂盒测定蛋白浓度，计算每个泳道的上样量为70 μg总蛋白，计算5× loading buffer量及超纯水量，定 …
WebJul 26, 2024 · Expression profiling of cisplatin resistant cells derived from H460 lung cell line. Organism: Homo sapiens: Experiment type: Expression profiling by array: … simplicef side effects for dogsWebNov 5, 2024 · Oroxylin A attenuates hypoxia-induced cisplatin resistance a H460 cells were treated with cisplatin under normoxic (20% O2) or hypoxic (1% O2) condition for 36 h. The cell viability was analyzed ... simplicial attention networksWebCisplatin induces A549 and H460 cell apoptosis via the mitochondrial‑associated pathway (A and B) After treatment with 10, 20 and 40 µM cisplatin, cell apoptosis was detected using flow... raymarine ar200 bus not connectedWebJun 20, 2024 · H460-Cis and A549-Cis cells were treated with 2 μ g/mL cisplatin to maintain cisplatin resistance character. All human cell lines have been authenticated using short tandem repeat (STR) profiling. Cells were maintained at 37°C in a humidified atmosphere with 5% CO 2. simplicef useWeb目的 基于基因芯片数据分析非小细胞肺癌H460细胞株顺铂耐药相关的靶基因及信号传导通路.方法 从基因表达数据库 (GEO)下载基因芯片数据,数据预处理后,使用R软件分析H460顺铂耐药细胞株与亲本细胞株中差异表达的基因.运用生物医学信息学方法 (基因本体论使用 ... simplicial activity driven modelWebApr 9, 2024 · In vitro cytotoxicity of free cisplatin and G4.0-PAA/aquated cisplatin nano-complex against NCI H460 cells (human lung cancer cells) was evaluated by SRB assay, and their corresponding IC 50 values were calculated from the dose–response curves using non-linear regression analysis. The cells were incubated for 5 h at pH 7.4 in the … simplic gmbh hildesheimWebJul 15, 2011 · Effects of Cav-1 on cisplatin-induced H460, H460/Cav-1, and H460/shCav-1 cell death. a Cells were treated with various concentrations of cisplatin (0–250 μM) for 24 h, and then cell viability was determined by XTT assay.b, d Apoptotic cell death was detected by Hoechst 33342 staining assay, counted the cells and performed as % apoptosis.c Cav … simplicial approximation theorem