Chitinase-3-like protein 1
WebNational Center for Biotechnology Information WebIntroduction. Chitinase-3-like protein 1 (CHI3L1), also known as YKL-40 and human cartilage glycoprotein-39 (HC-gp39), is a highly conserved glycoprotein that can bind to …
Chitinase-3-like protein 1
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WebBackground: Chitinase 3-like 1 protein (CHI3L1) (YKL-40 in humans and breast regression protein [BRP]-39 in mice) is required for optimal allergen sensitization and Th2 inflammation in various chronic inflammatory diseases including asthma. However, the role of CHI3L1 in airway inflammation induced by respiratory viruses has not been investigated. WebJan 1, 2024 · Protein S100-A9, Protein S100-A8, Chitinase-3-like protein 1, Haptoglobin, Integrin beta-2, and Chloride intracellular channel protein 1 were more abundant in milk …
WebBackground: Chitinase 3-like protein 1 (CHI3L1) is most likely a malignant tumor metastasis-associated gene. However, the functions of CHI3L1 in colon cancer cell proliferation and its cetuximab sensitivity are still unclear. We aimed to investigate the mechanism of CHI3L1 in promoting colon cancer cell proliferation and its sensitivity to … WebDiagnosis of cardiac surgery-associated acute kidney injury: differential roles of creatinine, chitinase 3-like protein 1 and neutrophil gelatinase-associated lipocalin: a prospective …
WebFeb 19, 2024 · Systemic sclerosis (SSc) is an autoimmune disease with completely undefined etiology and treatment difficulties. The expression of both protein coding and non-coding RNAs is dysregulated during disease development. We aimed to examine a possible regulatory axis implemented in the control of chitinase-3 like protein 1 … WebApr 6, 2024 · IntroductionPositive intracranial arterial remodelling is a dilated lesion of the large intracranial vessels; however, its pathogenesis is currently unknown. Some studies have identified chitinase-3 like-protein-1 (YKL-40) and matrix metalloproteinase (MMP)-9 as circulating inflammatory factors involved in positive vascular remodelling. Herein, we …
WebJohansen and Carretta et al. found that COS exerted their anti-tumorigenic effects through the inhibition of YKL-40 (also known as chitinase-3-like 1 or Chi3L1), which is a conserved, secreted chitinase-like protein (CLP) found in elevated levels in many diseases, including cancer [126,127].
WebMar 4, 2024 · Chitinase-3-like protein 1 (CHI3L1) was induced in both acute and chronic liver injuries, and recent studies reported that it possesses an immunosuppressive ability. CHI3L1 was also expressed in mesenchymal stem cells (MSCs), thus we investigates the role of CHI3L1 in MSC-based therapy for immune-mediated liver injury here. We found … greg anderson seattle police officerWebApr 5, 2024 · Chitinase-3-like protein 1 is an independent risk factor for the early failure of forearm autologous arteriovenous fistulas in uremic patients. Chitinase 3-like-1, Tolloid-like protein 1, and intergenic gene polymorphisms are predictors for hepatocellular carcinoma development after hepatitis C virus eradication by direct-acting antivirals. greg anderson wifeWebDec 1, 2024 · Chitinase-3 like-protein-1 (CHI3L1), a member of glycoside hydrolase family 18 including chitinases and non-enzymatic chitinase-like proteins, is a secreted molecule that plays an important role in cancer development, inflammatory diseases and oxidant injury via various mechanisms [8]. greg and fetchWebMar 8, 2024 · Chitinase-3-like 1 protein (YKL-40) is a secreted glycoprotein originally isolated from human osteosarcoma cells . YKL-40 is approximately 40 kDa in size and is … greg and georgie grand designs cancerWebJul 6, 2024 · Here, we show that chitinase-3-like 1 (CHI3L1), also known as human homolog YKL-40, predominately modulates the GBM TME using unbiased approaches. CHI3L1 signaling selectively regulates tumor infiltration and cell migration of MDMs and MG by forming distinct protein-binding complexes. greg and gina hartwickWebBackground: Chitinase 3-like 1. Chitinase 3-like 1 (CHI3L1), also called YKL-40 or human cartilage glycoprotein 39 (HCGP39), is a 39 kDa glycoprotein member of the glycosyl … greg and heather\\u0027s explorationsWebChitinase-3-like protein 1 (CHI3L1), also known as YKL-40, is a secreted glycoprotein that is approximately 40kDa in size that in humans is encoded by the CHI3L1 gene. The name YKL-40 is derived from the three N … greg and heather\u0027s explorations